toughadj.强硬的；棘手的，难办的；艰苦的；严厉的；牢固的，强壮的；坚强的，坚韧的adv.以强硬的态度；强硬地，顽强地n.暴徒; 恶棍tough out咬紧牙关挺过

1. Alcohol lowers resistance to illness.
   含酒精饮料会削弱对疾病的抵抗能力。
2. His resistance will break down in time.
   他的抵抗终究是会瓦解的。