It is possible that this might become more of an issue as the use of VEGF inhibitors expands and, we predict, will be an important class effect of these drugs. 随着血管内皮生长因子抑制剂的扩大利用，这有可能不止是一个问题，我们预测，这可能是这些药物的一类非常重要的作用。
VEGF-induced metastatic colonies were surrounded by densely packed stromal cells before detectable angiogenesis, suggesting that VEGF is involved in the initiation of desmoplasia. 在血管形成之前，引入血管内皮生长因子表达的转移灶被高密度的间质细胞包裹，表明血管内皮生长因子参与结缔组织增生的过程。
